Hunan Nubia black goat contagious pleuropneumonia, also known as the goat mycoplasma pneumonia caused by Mycoplasma, is a highly contagious diseases, main clinical features are high fever, cough, gasp, pleural happen serous and fibrinous inflammation, progressive weight loss, the mortality rate is high, 15% ~ 50%. Occurred in the spring and autumn and early winter.

A, pathogen and epidemic

The pathogen of Mycoplasma mycoides subspecies of goat, mycoplasma, mycoplasma. It is in disease material corruption can only live for 3 days, in 10 DEG to -12 DEG dark conditions can live for 50 days; heating to 50 DEG C, 40 minutes can be killed; 0.5% carbolic acid and 0.25% formalin treatment for 48 hours, can be killed. Sheep disease, disease of lung tissue disease of sheep, excretion and secretion and anti sheep is the main source of infection of the disease.

The disease is endemic, with contact infectious strong, can also be spread by air, through the respiratory tract infection. The cold humid climate of sheep, dark, wet cold continuous multi day overcast and rainy, flock density and poor nutrition, will trigger and aggravate the disease. Under natural conditions, the pathogen infect only goats, especially sheep onset under the age of 3 and more heavily. The flock if there is a Hair Coloring disease, such as control ineffective, generally 20 days can affect the whole flock.

Two, symptoms and differential diagnosis

The disease has a long incubation with 20 ~ 30 days, a short 4 days to 8 days, with an average of 18 days to 20 days. The most acute type sheep disease course was 1 days to 5 days, acute type was 10 ~ 30 days, chronic type can be as long as several months. Sheep onset temperature is elevatory, spirit depressed, appetite decreasing, followed by cough, outflow serous rhinorrhea; from 4 days to 5 days after the cough, a dry cough and pain, serous sticky purulent rhinorrhea, adhesion on the nose, upper lip, such as rust. A sick sheep is pleuropneumonia change; percussion dullness; bronchial breath sounds auscultation and fricative; contact pressure chest wall disease of sheep, sensitive reaction, pain. Disease of sheep difficulty breathing, high fever, eyelid edema, tears, and some sticky purulent secretion, back arched, the expression of pain. Pregnant ewes infected much abortion; some Montenegro Morel distension diarrhea, some sheep disease oral ulceration, lips, etc. the breast skin rash. Disease of sheep temperature dying will drop to below normal temperature. Necropsy disease (death): lesions confined to the sheep visible chest, the chest cavity with yellowish effusion, for the side of lung lesion, a fibrinous pneumonia, there are two sides of pneumonia; lung tissue of hepatic amyloidosis, section such as the marble; pulmonary lobule interstitial change width, boundaries clear; endovascular multiple formation thrombosis, pleural thickening and pleural adhesions and rough, more, heart capsule; bronchial lymph nodes and mediastinal lymph nodes, section of fluid, bleeding points; pericardial effusion, myocardial relaxation, become soft; liver and spleen enlargement; gallbladder swelling; renal enlargement, subcapsular bleeding dots; chronic illness sheep liver variable area machine, connective tissue hyperplasia, the formation of necrosis like cyst. This ill clinical and pathology with goat Pasteurellosis similar, should undertake pathology microscopy can accurately distinguish; with diseased inoculated rabbits or mice, caused by experimental animal of onset of pasteurellosis, but this will not cause the pathogen tested animal, the incidence of dyeing.

Three, a comprehensive prevention and control

(a), preventive measures

1 not to purchase commodity sheep introduction or epidemic area.

2 purchased sheep should be isolated remote feeding quarantine for more than 1 months, no disease can determine the group mixed feeding.

3 adhere to farrow. Sheep have blight (households) to do cleaning work.

4 found should be promptly on the incidence of disease of sheep flock isolation, blockade and treatment, the mortality of sheep as soon as harmless treatment. Sheep farms (households) the incidence of pens, sink, manger, appliance and ground to use 10% ~ 20% lime milk or 10% of bleaching powder solution disinfection of 1 ~ 2 times. Fecal excretion and secretion to keep a thorough cleaning and buried 1 meters deep underground or under the seal of high temperature fermentation processing.

5 strengthening feeding management, keep the environment clean sanitation, wash pad material, pay attention to ventilation, and do a good job in daily disinfection, especially black goat sheep and feeding apparatus. Usually every 6 to 7 days of pens, utensils disinfection with 10% bleach solution 1.

6 the regular sheep inoculated goats contagious pleuropneumonia inactivated aluminum hydroxide vaccine, following 6 months of goat each subcutaneous or intramuscular inoculation of 3 ml, 6 months above goat each inoculated with 5 ml, the immune protection period of up to 1 years.

(two), treatment method

1 western medicine treatment: 5 mg per kg body weight to 10 mg oxytetracycline, 2 times daily intravenous or intramuscular injection, once every 7 to 10 days. Intramuscular injection of the 10% sulfadiazine injection, each 10 ml, 2 times a day, for 4 days to 5 days. The per kg body weight daily tetracycline 30 ml ~50 ml, 2 times orally, for 4 to 5 days. The new arsphenamine, adult sheep medicine 0.3 grams to 0.5 grams, May age below 0.1 sheep to 0.2 grams in May, above the age of young sheep 0.3 grams to 0.4 grams, the drug dissolved in 7 ml to 10 ml glucose saline, disposable slow intravenous injection, ill sheep every 3 days to 4 days after medication 1 (but the dosage to slightly less), the curative effect can reach more than 90%.

2 Chinese medicine treatment: 1. The following 4 sheep doses for 1 days: 30 grams, 30 grams of Scutellaria Radix Peucedani, Radix 30 grams, 30 grams of white peony root, phellodendron bark 30 grams, Banlangen 40 grams, 30 grams, 50 grams of Aster the Divine Comedy, gardenia 30 grams, bupleurum 30 grams, almond 30 grams, 50 grams of hawthorn, forsythia 30 grams, 30 grams of Schizonepeta tenuifolia, pummelo peel 30 grams, 50 grams of malt, honeysuckle 30 grams, 30 grams of citrus aurantium