Escherichia coli mastitis is the Nubian ewes adversely feeding management or decreased resistance in the postpartum body condition, pathogenic Escherichia coli invade the body milk, blood and lymph fluid caused by breast tissue inflammation, often show acute after. The prevalence of ewes increased body temperature, anorexia, spirit depressed, lethargy, accelerated heart rate, shock and even death, milk into a watery serous secretion.

1.2, laboratory examination

Sterile take ipsilateral breast milk smear, Gram staining microscopic examination, visible gram negative, thick and short, blunt ends of small bacilli.

1.3, diagnosis and treatment

Palpation of breast have fever, swelling and other symptoms. Treatment with antibacterial and anti-inflammatory, antipyretic and analgesic, improve blood circulation supplement. With flunixin meglumine 1 ~ 2mg/kg body weight intravenously; systemic antibiotics intravenous injection of 10mg/kg; with 5% hypertonic saline solution (HSS) intravenous injection, the dose of 5kg/mL. If necessary, can carry out transfusion therapy. Should avoid the use of aminoglycoside antibiotics on sheep.

2, gangrenous mastitis

2.1, clinical symptoms

At the beginning of the disease affected areas is swollen, hard, heat, pain, suffering from sheep body temperature may rise to 41 DEG C, respiration, pulse speed, no appetite, do not let the lamb is close to the breast, stiff gait or significant claudication. To reduce the amount of subsequent lactation, ipsilateral breast enlargement, harden. Breast redness of skin hyperemia; pale blue dot appears some congestion area, 2 ~ 3D after the inflammatory edema spread to the abdominal wall and limbs. 3 ~ 4D after breast began to appear gangrene, skin browning, cold. The onset of lactation sheep sheep accounted for more than 10%, the mortality rate of up to 50% ~ 70%.

2.2, laboratory examination

Pathogen Staphylococcus aureus, from the diseased breast can also isolate of Staphylococcus aureus and Staphylococcus epidermidis.

2.3, diagnosis and treatment

According to the main clinical symptoms, such as body temperature, appetite waste must, at the same time as the basis for diagnosing breast acute inflammation. Systemic treatment with antibiotics (penicillin, streptomycin) and sulfathiazole have good curative effect. Dosage: 40 * l04IU for penicillin LG, streptomycin, sulfathiazole 0.03 ~ 0.04g/kg body weight, every 6 ~ 8h for the 1 time, for 3 ~ 4D. Of acute gangrenous cases should be immediately isolated ewe. Chronic cases sheep no therapeutic value, should be promptly eliminated. In severe cases, can be combined with the application of penicillin and sulphathiazole, or penicillin and streptomycin. Local treatment available antibiotics or sulfa drugs milk tank injection.

3, subclinical mastitis

3.1, clinical symptoms

Subclinical mastitis is reduce breast inflammation sheep production performance. Symptoms of breast abscess, edema and decay, then appear purulent exudate, resulting in poor growth of lamb, malnutrition, or even starve to death.

3.2, laboratory examination

Sheep caused by subclinical mastitis by many bacteria, including Bacillus, Escherichia coli, purulent actinomycetes, pseudo tuberculosis Actinomyces and other environmental pathogens. Differential diagnosis of acute bacterial requirements of Microbiology experiment.

3.3, diagnosis and treatment

Through the breast abscess, edema and decay, then appear purulent exudate to make a diagnosis.

(1), crowded over milk, 0.5% oxacillin sodium solution 5 ~ 10 mL from the nipple to the inflammation of the mammary chamber injection, 2 /d. It could be combined with systemic therapy, intramuscular injection or intravenous injection of 0.5% sodium oxacillin water solution of 15 mg/kg, 2 /d, used 3D for 1 courses.

(2), crowded over milk, 0.5% gentamicin sulfate water solution 5 ~ 10 mL from the nipple to the inflammation of the mammary chamber injection, 1 times a day. At the same time, can be combined with systemic therapy, intramuscular injection or intravenous injection of 15 mg/kg of 0.5% sodium oxacillin aqueous solution, 2 times /d, used 3D for 1 courses.

(3), treatment of acute mastitis, available physiological saline 15 ~ 20 mL, vitamin C 3 ~ 5 mL, 0.25% of 10 ~ 15 mL procaine penicillin, 30 * L04 to 50 * L04 IU, ill sheep blood 10mL, more drug mixture in the ward around along the disease tissue and healthy tissue was injected, effect of satisfactory.

4, Mycoplasma mastitis

4.1, clinical symptoms

In the spring of multiple, breast infections occur in the last 3 months of pregnancy. Mycoplasma agalactiae and enter the bloodstream, causing secondary infection septicaemia, lesions can occur in the breast, uterine, eyes and joint. Patient body temperature reaches 41 to 42 DEG C, loss of appetite, breast atrophy, the sharp decline in the volume of lactation.

4.2, laboratory examination

Mycoplasma pneumoniae is an important pathogen which caused goat mastitis, gram negative, the most suitable growth temperature of 37 DEG C, does not grow at a temperature of 28 DEG C, the surfactant and lipid solvent is extremely sensitive, exhibited hemolytic on blood agar. Low temperature resistant, resistant to moisture, minus 20 degrees can survive for several months, can be separated from the breast, blood, organs, reproductive organs, the respiratory organs, abortion, joint.

4.3, diagnosis and treatment

The milk of purulent secretion exudate, condensed milk, milk volume decreased significantly, breast enlargement of lymph nodes, systemic diseases such as arthritis, pneumonia, Mycoplasma mastitis incidence of conjunctivitis is the characteristic. The bacterial culture was negative, antibiotic treatment is invalid. Through the Taimulin, tylosin 20mg/kg, intramuscular injection, 2 times /d, erythromycin 3 ~ 5mg/kg, intramuscular injection, 2 /d, or tetracycline 10mg/kg intramuscular injection, 1 /d treatment.

5, virus mastitis

5.1, clinical symptoms

Infection in Hunan black goat progressive pneumonia virus (OPPV), breast engorgement but palpate hard, milk yield declined significantly, nipple withered. 3 years old of above the highest incidence of breast milk of sheep, the color and the content is normally.

5.2, laboratory examination

There are many OPPV diagnostic methods, including culture, virus isolation